On the medal begin with this prayer.
O God, who gave to Saint Peregrine an Angel for his companion, the Mother of God for his Teacher, and Jesus as the Physician of his malady, grant we beseech You through his merits that we may on earth intensely love our holy Angel, the blessed Virgin Mary, and our Saviour, and in Him bless them forever. Grant that we may receive the favor which we now petition. We ask this through the same Christ our Lord. Amen

On the beads pray
Seven Our Fathers, seven Hail Marys and seven Glory be to the Fathers with the invocation, St. Peregrine, pray for us.